|
T4007 |
Eticlopride hydrochloride
|
|
Dopamine Receptor
|
|
Eticlopride, an antipsychotic, is a Selective dopamine D2/D3 receptor antagonist (Ki: 0.5/0.16 nM). |
|
T9228 |
Propionylpromazine hydrochloride
|
Propiopromazine hydrochloride |
Dopamine Receptor
|
|
Propionylpromazine hydrochloride (Propiopromazine hydrochloride) is a dopamine receptor D2 (DRD2) antagonist. |
|
T11799 |
L-745870 hydrochloride
|
|
Dopamine Receptor
|
|
L-745870 hydrochloride has excellent brain penetration. L-745870 hydrochloride is a high-affinity, selective and orally active human dopamine D4 receptor antagonist with a Ki of 0.43 nM, and considerably weaker D2 recept... |
|
T6604 |
Nepicastat hydrochloride
|
Nepicastat HCl,RS-25560-197 hydrochloride,SYN-117 hydrochloride,Nepicastat (SYN-117) HCl |
Hydroxylase
|
|
Nepicastat hydrochloride (RS-25560-197 hydrochloride) is an effective and specific inhibitor, which is used for bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively.The affinity of Nepicasta... |
|
T39429 |
AHN 1-055 hydrochloride
|
3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride |
Dopamine Receptor
|
|
AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM). |
|
T7553 |
(+)-PD 128907 hydrochloride
|
|
Dopamine Receptor
|
|
(+)-PD 128907 hydrochloride is an agonist of D3 dopamine receptor . |
|
T7180 |
Sultopride hydrochloride
|
LIN-1418 hydrochloride |
Dopamine Receptor
|
|
Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective dopamine D2 and D3 receptor antagonist. |
|
T4081 |
MPTP hydrochloride
|
MPTP-hydrochloride |
Apoptosis
,
Dopamine Receptor
|
|
MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability. MPTP hydrochloride is toxic to dopaminergic neurons, which can lead to Parkinson's disease, and is widely used in th... |
|
T1292 |
Tiapride hydrochloride
|
|
Dopamine Receptor
|
|
Tiapride is a selective blocker of D2/3 dopamine receptors in the brain. It is used in the therapy of various psychiatric and neurological disorders containing dyskinesia, negative symptoms of psychosis, alcohol withdraw... |
|
T10683 |
Carmoxirole hydrochloride
|
EMD 45609 hydrochloride |
Dopamine Receptor
|
|
Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo. |
|
T0766 |
Promazine hydrochloride
|
Romtiazin hydrochloride,Sinophenin hydrochloride |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
,
AChR
|
|
Promazine hydrochloride (Romtiazin hydrochloride) is a phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as ... |
|
T9272 |
Xaliproden hydrochloride
|
|
Dopamine Receptor
,
5-HT Receptor
|
|
Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist. |
|
T14767 |
BP 897 hydrochloride
|
|
Dopamine Receptor
|
|
BP 897 is a potent and selective agonist of dopamine D3 receptor and it is a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors. Which shows low affinities at D1 and D4 receptors ... |
|
T2574 |
Alizapride hydrochloride
|
Alizapride HCl |
Dopamine Receptor
|
|
Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea and vomiting. |
|
T0716 |
Molindone hydrochloride
|
EN-1733A |
Dopamine Receptor
,
5-HT Receptor
,
AChR
|
|
Molindone hydrochloride (EN-1733A) is an indole derivative effective in schizophrenia and other psychoses by blocking the effects of dopamine in the brain. |
|
T10758L |
Centanafadine hydrochloride
|
EB-1020 hydrochloride |
Dopamine Receptor
,
Serotonin Transporter
,
Adrenergic Receptor
,
Norepinephrine
|
|
Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin... |
|
T6988 |
SKF 38393 hydrochloride
|
(±)-SKF-38393 hydrochloride,SKF-38393A,SKF38393 HCl |
Dopamine Receptor
|
|
SKF 38393 hydrochloride (SKF38393 HCl) is a selective dopamine D1/D5 receptor agonist. |
|
T5009 |
Trimethobenzamide hydrochloride
|
Ro 2-9578,Tribenzagan Hydrochloride |
Dopamine Receptor
,
Influenza Virus
|
|
Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting. |
|
T3526 |
Dasotraline hydrochloride
|
SEP-225289 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
,
Serotonin Transporter
,
Norepinephrine
|
|
Dasotraline hydrochloride (SEP-225289 hydrochloride) (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respe... |
|
T2092 |
Amitifadine hydrochloride
|
DOV-21947 hydrochloride,EB-1010 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
,
Serotonin Transporter
,
Norepinephrine
|
|
Amitifadine hydrochloride (EB-1010 hydrochloride) is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). |
|
T8382 |
Cariprazine hydrochloride
|
Cariprazine HCl,RGH188 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
|
|
Cariprazine hydrochloride (RGH188 hydrochloride) is an antipsychotic drug, is a D3 and D2 receptor partial agonist((Ki of 0.085 nM and 0.49 nM, respectively) |
|
T0068 |
Fluphenazine dihydrochloride
|
Prolixin,Fluphenazine hydrochloride |
Dopamine Receptor
|
|
Fluphenazine dihydrochloride (Prolixin) is an inhibitor of phenothiazine-class D1DR and D2DR; In studies, Fluphenazine can be used to probe the effects and metabolic process of this commonly used dopamine antagonist. |
|
T2592 |
Ropinirole hydrochloride
|
SKF 101468 hydrochloride,SKF-101468A,Ropinirole HCl |
Dopamine Receptor
|
|
Ropinirole hydrochloride (SKF-101468A) is a selective dopamine D2 receptors agonist (Ki: 29 nM). Ropinirole hydrochloride (SKF-101468A) is the hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with anti... |
|
T3431 |
Pardoprunox hydrochloride
|
SLV-308 hydrochloride,DU-126891 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
|
|
Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A recept... |
|
T7745 |
Diclofensine hydrochloride
|
Ro 8-4650 hydrochloride |
Others
,
Dopamine Receptor
|
|
Diclofensine hydrochloride (Ro 8-4650 hydrochloride) is a Novel Antidepressant, on Peripheral Adrenergic Function |
|
T4369 |
SCH-23390 hydrochloride
|
R-(+)-SCH23390 hydrochloride |
Potassium Channel
,
Dopamine Receptor
,
5-HT Receptor
|
|
SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM). |
|
T8136 |
Perospirone hydrochloride
|
Perospirone HCl,SM-9018 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
|
|
Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist. |
|
T1735 |
Lurasidone hydrochloride
|
Lurasidone HCl,SM-13496 (Hydrochloride),SM-13496 |
Dopamine Receptor
,
5-HT Receptor
,
Norepinephrine
|
|
Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor antagonist, serotonin 5-HT7 receptor antag... |
|
T0074L |
Chlorprothixene hydrochloride
|
NSC 78193,Minithixen,Truxal hydrochloride,NSC 56379,NSC 169899,Minithixen hydrochloride |
Dopamine Receptor
,
5-HT Receptor
,
Antibacterial
,
AChR
,
Histamine Receptor
|
|
Chlorprothixene hydrochloride (Truxal hydrochloride) brings strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. Chlorprothixene hydrochloride s a typical an... |
|
T0031 |
Ziprasidone hydrochloride monohydrate
|
CP 88059 |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
,
Norepinephrine
,
Histamine Receptor
|
|
Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic activity. |
|
T0031L |
Ziprasidone hydrochloride
|
CP-88059 hydrochloride,CP-88059,Ziprasidone HCl |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
,
Norepinephrine
,
Histamine Receptor
|
|
Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity. |
|
T1069 |
Metoclopramide hydrochloride
|
Maxolon,Metoclopramide HCl |
Dopamine Receptor
,
5-HT Receptor
,
AChR
|
|
Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic. |
|
T12352 |
Oxidopamine hydrochloride
|
6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride |
Mitophagy
,
Dopamine Receptor
,
Autophagy
|
|
Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist. |
|
T5380 |
Ansofaxine hydrochloride
|
LPM570065,LY03005 |
Dopamine Receptor
,
5-HT Receptor
,
Norepinephrine
|
|
Ansofaxine hydrochloride (LY03005) is a serotonin-norepinephrine-dopamine reuptake inhibitor (IC50s: 723, 763 and 491 nM, respectively). |
|
T0365 |
Thioridazine hydrochloride
|
Mellaril,Aldazine |
Apoptosis
,
Potassium Channel
,
Dopamine Receptor
,
5-HT Receptor
,
Antibacterial
,
Adrenergic Receptor
,
Autophagy
|
|
Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4 selectivity. |
|
T8385 |
Metoclopramide hydrochloride hydrate
|
Metoclopramide monohydrochloride monohydrate |
Dopamine Receptor
,
5-HT Receptor
|
|
Metoclopramide hydrochloride hydrate (Metoclopramide monohydrochloride monohydrate) is a dopamine D2 antagonist that is a drug used for digestive dysfunction. It acts as an anti-emetic |
|
T1552 |
Itopride hydrochloride
|
HSR803,Ganaton |
Dopamine Receptor
,
AChE
|
|
Itopride hydrochloride (Ganaton) is an AChE and D2DR inhibitor. |
|
T21446 |
Rotigotine Hydrochloride
|
Rotigotine (Hydrochloride),N 0923,N-0924,Rotigotine HCl,N-0923 |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
|
|
Rotigotine Hydrochloride (N-0924), a dopamine receptor agonist prefering for D3 receptors over D1 and D2, has effective activity of anti-Parkinsonian. Racemic rotigotine hydrochloride is about 50 times as potent as quinp... |
|
T24047 |
Etilevodopa hydrochloride
|
Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester |
Others
,
Dopamine Receptor
,
Drug Metabolite
|
|
Etilevodopa hydrochloride (L-DOPA ethyl ester) is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration. |
|
T0991 |
Desipramine hydrochloride
|
NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020 |
Dopamine Receptor
,
5-HT Receptor
,
Serotonin Transporter
,
Adrenergic Receptor
|
|
Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-upt... |
|
T0302 |
Triflupromazine hydrochloride
|
Neoprin,Fluopromazine hydrochloride,Fluorofen,Flumazin |
Dopamine Receptor
,
5-HT Receptor
,
AChR
,
Autophagy
|
|
Triflupromazine hydrochloride (Fluopromazine hydrochloride), an antipsychotic medication, is Dopamine D1/D2 receptor antagonists. |
|
T21782 |
A 77636 hydrochloride
|
A77636 hydrochloride |
Dopamine Receptor
|
|
A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM). A 77636 hydrochloride shows antiparkinsonian activity. A 77636 hydrochloride is functionall... |
|
T22817 |
GSK 789472 hydrochloride
|
GSK-789472 HCl,1-phenyl-3-(piperidin-2-ylmethyl)imidazolidin-2-one hydrochloride,4,5-Dihydro-1-phenyl-3-(2-piperidinyl)methylimidazol-2(1H)-one |
Dopamine Receptor
|
|
GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist. |
|
T11238L |
Etamicastat hydrochloride
|
BIA 5-453 hydrochloride |
Dehydrogenase
|
|
Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension. |
|
T7433 |
2-Phenylethylamine hydrochloride
|
&beta,-Phenylethylamine hydrochloride,benzeneethanamine hydrochloride,&beta,-aminoethylbenzene hydrochloride |
Others
|
|
2-Phenylethylamine hydrochloride (benzeneethanamine hydrochloride) acts as neuromodulator in the central nervous system. It stimulates the release of norepinephrine and dopamine and is metabolized by monoamine oxidases a... |
|
T23234 |
Rimcazole dihydrochloride
|
|
Others
|
|
Rimcazole dihydrochloride is the hydrochloride salt of Rimcazole, a σ receptor antagonist. Rimcazole dihydrochloride also binds to dopamine transporter proteins and inhibits dopamine uptake. |
|
T4274 |
Melitracen hydrochloride
|
Thymeol hydrochloride,Melixeran |
Dopamine Receptor
,
5-HT Receptor
|
|
Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression. |
|
T12510 |
PNU-177864 hydrochloride
|
PNU-177864 (hydrochloride) |
Dopamine Receptor
|
|
|
|
T0059 |
Diphenylpyraline hydrochloride
|
4-Diphenylmethoxy-1-methylpiperidine hydrochloride |
Histamine Receptor
|
|
Diphenylpyraline hydrochloride (4-Diphenylmethoxy-1-methylpiperidine hydrochloride) is used in the treatment of Parkinsonism.It is a first-generation antihistamine with anticholinergic effects, functions as a dopamine re... |
|
T8639 |
Phenibut (hydrochloride)
|
3-Amino-4-phenylbutyric acid hydrochloride |
GABA Receptor
|
|
Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates dopamine receptor... |
